Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: Aggregation of (a) CdSe-COOH QD and (b) CdSe-PDDA QD in seawater and the effect of humic acid. Error bars mean standard error.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques:

Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: Dissolution kinetics of CdSe-COOH in seawater under different light conditions. Error bars mean standard error.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques: Dissolution

Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: Sedimentation of CdSe-COOH and CdSe-PDDA in seawater and the effect of HA. V s (mm/d) is the sedimentation rate, C 0 (mg/L) is the concentration of QDs (i.e. total Cd) at the beginning of the experiment; C NS (mg/L) is the QD concentration after it reached equilibrium with the QD remaining in the supernatant considered as not settling.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques: Sedimentation, Concentration Assay

Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: Effect of humic acid on the dissolution kinetics of QDs: (a) the effect of both light condition and HA on CdSe-COOH dissolution and; (b) the effect of both surface coatings (i.e., -COOH and –PDDA) and HA. Error bars mean standard error.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques: Dissolution

Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: The toxicity of (a) dissolved cadmium and (b)CdSe-COOH nanoparticle. Error bars are standard error.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques:

Journal: Environmental science & technology

Article Title: Aggregation, sedimentation, dissolution and bioavailability of quantum dots in estuarine systems

doi: 10.1021/acs.est.6b04475

Figure Lengend Snippet: The LC50s of dissolved cadmium and CdSe-COOH nanoparticle.

Article Snippet: Three types of QDs were purchased from Ocean NanoTech (San Diego CA, USA): CdSe/ZnS QDs with carboxylic acid (CdSe-COOH), CdSe/ZnS QDs with a positively charged polydiallydimethylammounium (PDDA) surface (CdSe-PDDA), and CdSe water soluble QDs without the ZnS shell (CdSe-NS).

Techniques:

Journal: Nature Communications

Article Title: In vivo cation exchange in quantum dots for tumor-specific imaging

doi: 10.1038/s41467-017-00153-y

Figure Lengend Snippet: Breast tumor-specific imaging achieved by extravascular delivery of etchable ZHS-QDs. Mice bearing orthotopic MCF10CA1a human breast tumors received an intravenous injection of iRGD or PBS before an intravenous dose of ZHS-QDs. Ag-TS was given intraperitoneally. n = 4 per group. a The mice were anesthetized and imaged with a Li-Cor Pearl imager 40 min after etching. Arrows , tumors. b In situ NIR imaging of the mice after euthanasia and necropsy performed under deep anesthesia. c NIR images of collected tissues. d NIR signal per unit area in collected tissues ( left panel ) and T/Li ratio ( right panel ). B, brain; H, heart; Li, liver; S, spleen; Lu, lung; K, kidney; T, tumor. Statistics, two-way analysis of variance ( left panel ) or Student’s t -test ( right panel ); error bars , SEM; ns, not significant; * P < 0.05; *** P < 0.001. e Confocal micrographs of cultured MCF10CA1a cells treated with ZHS-QDs with or without free iRGD followed by etching with Ag-TS. Note that the QDs were internalized into the cells in the presence of iRGD, and that only the extracellular QDs were etched. Blue, Hoechst 33342; green, ZHS-QDs; scale bars , 50 μm. Insets show a magnified view of the boxed areas . f Epifluorescence micrographs of cultured PC-3 human prostate cancer cells treated with cell-penetrating QDs followed by etching with Ag-TS. PC-3 cells were incubated with CdSe/ZnS QDs coated with a cell-penetrating peptide KCDGRPARPAR. Only speckled peri-nuclear signals remain after etching. Scale bars , 50 µm. g The tumors shown in c were processed for immunofluorescence staining and subjected to confocal microscopy. Blue , DAPI; red , CD31 or α-SMA; green , ZHS-QDs; scale bars , 50 μm. The boxed area is magnified. Note that the QD signals are found in the perinuclear area of the cells

Article Snippet: CdSe/ZnS QDs coated with cell-penetrating KCDGRPARPAR peptides (LifeTein, Somerset, NJ) were prepared according to the manufacturer’s instructions associated with the eFluor 605NC sulfhydryl-reactive conjugation kit (eBioscience).

Techniques: Imaging, Injection, In Situ, Cell Culture, Incubation, Immunofluorescence, Staining, Confocal Microscopy